Babs Dionne, proud Franco-American, doting grandmother, and vicious crime matriarch, rules her small town of Waterville, Maine, with an iron fist. She controls the flow of drugs into Little Canada with the help of her friends and oldest daughter.

When a drug kingpin discovers his numbers are down in the upper Northeast, he sends a malevolent force, known only as "The Man," to investigate. At the same time, Babs's youngest daughter, Sis, has gone missing, which doesn't seem like a coincidence. In twenty-four hours Sis will be found dead, and the whole town will seek shelter from Babs’s wrath.